Multivitamins and Anti-oxidants

Since 2011 accumulating evidence has shown that multivitamins and antioxidants are not only not beneficial but may cause more harm.

The publication of the SELECT trial a few years before this is the first major trial to refute the benefits of vitamins and confirmed that Vit E and Selenium did not reduce the incidence and risk of prostate Ca.

The extended follow up of the SELECT trial showed further interesting results at that time in 2011. (see the links below)

To be noted are:

1. Daily vitamin E supplements in fact INCREASED men’s risk of prostate cancer as seen by the extended follow-up of the SELECT trial.
2. Vitamin supplements are ONLY known to prevent disease in people who have VITAMIN DEFICIENCIES; not normal people with adequate body vitamin levels. There was NO extra benefit in people who already get enough vitamins through their diet.
3. Vitamin E ALSO has NOT BEEN SHOWN to protect against HEART DISEASE, COLON CANCER OR LUNG CANCER.
4. On the other hand, there is a growing body of evidence suggesting supplements may be harmful in high doses.
5. The public should consult their doctors accordingly.

“There is a need for consumers to be skeptical of health claims for unregulated over-the-counter products in the absence of strong evidence of benefit demonstrated in clinical trials”

Vitamins have been shown to be of benefit ONLY for:

1. Pregnancy – hematinics and folic acid
2. Cardiac disease – omega fatty acids

3.Some group of people – Calcium and Vit D

The other benefits are only as replacement therapy and not supplementation therapy as in nutritional disorders, after extensive intestinal surgery, etc.

This is discussed in the paper on Dietary Supplements and Mortality rates in the Iowa Women’s Health Study in the publication of Archives of Internal Medicine 2011 which supplements the extended SELECT study results

Access the links below:

http://drrajeenmalaysianurology.blogspot.my/2011/12/vitamin-e-and-incidence-of-prostate.html?m=1

http://jama.jamanetwork.com/mobile/article.aspx?articleid=1104493

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765487/?report=classic

https://www.bbc.com/future/article/20161208-why-vitamin-supplements-could-kill-you

http://www.m.webmd.com/a-to-z-guides/news/20131216/experts-dont-waste-your-money-on-multivitamins

http://www.ncbi.nlm.nih.gov/pubmed/22534785

 

 Read the following Healthline article:

https://www.healthline.com/nutrition/antioxidant-supplements

Should You Take Antioxidant Supplements?

Antioxidant supplements are popular and commonly considered healthy.

In part, this is because fruits and vegetables, which are rich in antioxidants, are associated with many health benefits, including a reduced risk of disease.

Yet, there is strong evidence to suggest that you may be doing your health a disservice by supplementing with antioxidants.

This article explains what antioxidant supplements are and why it’s better to get your antioxidants from food.

What Are Antioxidant Supplements?

Antioxidant supplements contain concentrated forms of antioxidants, which are substances that stabilize free radicals.

Your body naturally produces free radicals when you exercise and digest food.

Environmental factors, such as UV exposure, air pollutants, tobacco smoke and industrial chemicals like pesticides, are also sources of free radicals.

If free radicals exceed your body’s ability to regulate them, a condition called oxidative stress occurs. Over time, this contributes to aging and the development of diseases, including cancer.

The main antioxidants that help regulate free radicals in your body are the vitamins A, C, and E and the mineral selenium.

Antioxidant supplements contain 70–1,660% of the daily value (DV) of these key nutrients.

It’s commonly thought that taking antioxidant supplements prevents the damage caused by free radicals to the body’s cells, thereby promoting longevity and warding off disease.

However, taking antioxidant supplements in high amounts can do just the opposite.

Summary

Antioxidant supplements contain concentrated forms of antioxidants, which are substances that keep your body’s cells healthy by combating damage caused by free radicals.

Taking High Doses Can Be Harmful

The health detriments associated with taking antioxidant supplements outnumber its potential benefits.

Taking antioxidant supplements in large doses is not recommended for many reasons.

May Decrease Exercise Performance

Your body naturally produces free radicals as a byproduct of energy metabolism during exercise. The harder and longer you exercise, the more free radicals your body produces.

Because free radicals can contribute to muscle fatigue and damage, it’s been proposed that taking antioxidant supplements can blunt their harmful effects, hence improving exercise performance and muscle recovery.

However, several studies have shown that taking antioxidant supplements — specifically vitamins C and E — can interfere with how your body adapts to exercise and even eliminate some of the health benefits associated with exercise.

May Increase Cancer Risk

The oxidative stress caused by free radicals to the body’s cells is thought to be a major contributor to the development of cancer.

Since antioxidants neutralize free radicals, taking antioxidant supplements have been speculated to decrease the risk of developing or dying from cancer.

Several meta-analyses, however, have shown that taking antioxidant supplements does neither reduce the risk of many types of cancers nor reduce the risk of dying from them once diagnosed, In fact, they may even increase the risk of certain cancers.

In addition, several meta-analyses have found that beta-carotene supplements, a precursor of vitamin A, increases the risk of bladder cancer, and, in people who smoke, the risk of lung cancer as well.

The exception is selenium, which may help prevent cancer in people with low levels of the mineral or in people with an elevated risk of cancer. However, more research is needed before selenium can be recommended for this purpose.

May Cause Birth Defects

Vitamin A is important for fetal growth and development, but at high doses, vitamin A supplements can increase the risk of birth defects.

Therefore, women who might be or are pregnant should not take high doses of vitamin A supplements.

These supplements are only recommended for pregnant women in areas where vitamin A deficiency is prevalent, such as in Africa and Southeast Asia.

Beta-carotene, the precursor of vitamin A, is not shown to lead to birth defects. But since taking the supplement long-term is associated with cancer, pregnant women should consult with their physician before taking beta-carotene supplements.

Summary

While they’re thought to be healthy, taking antioxidant supplements may reduce the health benefits of exercise and increase the risk of certain cancers and birth defects.

Vitamin C May Benefit Some People

Though antioxidant supplements are generally not recommended for a variety of reasons, the antioxidant vitamin C may benefit people with the common cold or those who smoke.

Vitamin C for the Common Cold

Vitamin C has not been shown to prevent the common cold, but it may reduce its severity and duration.

In a meta-analysis in more than 11,000 people, taking vitamin C supplements was shown to decrease the duration of colds by 8% while also decreasing its severity.

It’s best to take vitamin C in smaller doses — usually less than one gram — as its absorption decreases with higher doses. In addition, higher doses may cause stomach upset.

Smoking Increases Vitamin C Needs

Smoking causes many types of cancers, largely because cigarette smoke contains toxins that cause oxidative damage to your body’s cells.

Because of this increased exposure to free radicals, research suggests that people who smoke need 35 mg more of vitamin C per day than people who don’t smoke. Similarly, exposure to secondhand smoke also increases vitamin C needs.

Yet, this additional need for vitamin C can be easily met through diet and without taking antioxidant supplements.

Summary

For the most part, the use of antioxidant supplements is discouraged, though the antioxidant vitamin C can benefit people with the common cold or those who smoke. Still, needs can often be met through diet instead of supplements.

Get Your Antioxidants From Food

Getting antioxidants from food rather than supplements is much safer and healthier.

All foods contain different antioxidants in varying amounts, so it’s important to include a variety of foods in your diet.

While animal-based products, such as eggs and dairy products, have antioxidants, plant-based foods are particularly high in them.

These plant-based foods include:

• Vegetables: Broccoli, bell peppers, spinach.
• Fruits: Oranges, apples, berries.
• Whole-grains: Oats, quinoa, brown rice.
• Beans: Kidney, pinto, red beans.
• Nuts: Walnuts, pecans, almonds.
• Drinks: Coffee, tea.

Summary

Antioxidants are found in most foods, but plant-based sources such as fruits and vegetables are particularly rich in them.

The Bottom Line

Antioxidant supplements are commonly considered healthy but can be problematic when taken in excess.

They may decrease exercise benefits and increase your risk of certain cancers and birth defects.

Generally, it’s much better to get the antioxidants your body needs through a healthy diet.